<em>α</em>-Glucosidase Inhibitory Constituents from <em>Acanthopanax senticosus</em> Harm Leaves
<em>α</em>-Glucosidase Inhibitory Constituents from <em>Acanthopanax senticosus</em> Harm Leaves
Blog Article
A new triterpene glycoside, 3-<em>O</em>-[(<em>α</em>-L-rhamnopyranosyl)(1→2)]-[<em>β</em>-D-glucuronopyranosyl-6-<em>O</em>-methyl ester]-olean-12-ene-28-olic acid (<strong>1</strong>) and a new indole alkaloid, 5-methoxy-2-oxoindolin-3-acetic acid methyl ester (<strong>5</strong>) were isolated from the leaves of <em>Acanthopanax senticosus</em> Ring Holder Harms along with six known compounds.The structures of the new compounds were determined by means of 2D-NMR experiments and chemical methods.All Heart Dish the isolated compounds were evaluated for their glycosidase inhibition activities and compound <strong>6</strong> showed significant <em>α</em>-glucosidase inhibition activity.